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Tramadol Linked to Higher Mortality in Osteoarthritis (Klik hier) ENG
The authors note that tramadol, a weak opioid agonist, “has been considered a potential alternative to NSAIDs and traditional opioids because of its assumed relatively lower risk of serious cardiovascular and gastrointestinal adverse effects than NSAIDs, as well as a lower risk of addiction and respiratory depression compared with other opioids” and that tramadol prescriptions for OA have been increasing since 2000.
EDS-Foundation Netherlands 